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Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells

Adult skeletal muscle maintenance and regeneration depend on efficient muscle stem cell (MuSC) functions. The mechanisms coordinating cell cycle with activation, renewal, and differentiation of MuSCs remain poorly understood. Here, we investigated how adult MuSCs are regulated by CDKN1c (p57(kip2)),...

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Detalles Bibliográficos
Autores principales: Mademtzoglou, Despoina, Asakura, Yoko, Borok, Matthew J, Alonso-Martin, Sonia, Mourikis, Philippos, Kodaka, Yusaku, Mohan, Amrudha, Asakura, Atsushi, Relaix, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172026/
https://www.ncbi.nlm.nih.gov/pubmed/30284969
http://dx.doi.org/10.7554/eLife.33337