Cargando…
A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle
Chromosome 17q12–21 remains the most highly replicated and significant asthma locus. Genotypes in the core region defined by the first genome-wide association study correlate with expression of 2 genes, ORM1-like 3 (ORMDL3) and gasdermin B (GSDMB), making these prime candidate asthma genes, although...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172038/ https://www.ncbi.nlm.nih.gov/pubmed/29307657 http://dx.doi.org/10.1016/j.jaci.2017.12.974 |