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A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle
Chromosome 17q12–21 remains the most highly replicated and significant asthma locus. Genotypes in the core region defined by the first genome-wide association study correlate with expression of 2 genes, ORM1-like 3 (ORMDL3) and gasdermin B (GSDMB), making these prime candidate asthma genes, although...
Autores principales: | Stein, Michelle M., Thompson, Emma E., Schoettler, Nathan, Helling, Britney A., Magnaye, Kevin M., Stanhope, Catherine, Igartua, Catherine, Morin, Andreanne, Washington, Charles, Nicolae, Dan, Bønnelykke, Klaus, Ober, Carole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172038/ https://www.ncbi.nlm.nih.gov/pubmed/29307657 http://dx.doi.org/10.1016/j.jaci.2017.12.974 |
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