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Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function

Plasma cell survival and the consequent duration of immunity vary widely with infection or vaccination. Using fluorescent glucose analog uptake, we defined multiple developmentally independent mouse plasma cell populations with varying lifespans. Long-lived plasma cells imported more fluorescent glu...

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Detalles Bibliográficos
Autores principales: Lam, Wing Y., Jash, Arijita, Yao, Cong-Hui, D’Souza, Lucas, Wong, Rachel, Nunley, Ryan M., Meares, Gordon P., Patti, Gary J., Bhattacharya, Deepta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172041/
https://www.ncbi.nlm.nih.gov/pubmed/30157439
http://dx.doi.org/10.1016/j.celrep.2018.07.084