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Simvastatin functions as a heat shock protein 90 inhibitor against triple‐negative breast cancer

Acetylation plays an important role in regulating the chaperone activity of heat shock protein 90 (Hsp90) during malignant transformation through the stabilization and conformational maturation of oncogenic proteins. However, the functional acetylation sites, potential anticancer drug targets, are s...

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Detalles Bibliográficos
Autores principales: Kou, Xinhui, Jiang, Xiaoxiao, Liu, Huijuan, Wang, Xuan, Sun, Fanghui, Han, Jiami, Fan, Jiaxing, Feng, Guize, Lin, Zhaohu, Jiang, Lan, Yang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172049/
https://www.ncbi.nlm.nih.gov/pubmed/30039622
http://dx.doi.org/10.1111/cas.13748