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Simvastatin functions as a heat shock protein 90 inhibitor against triple‐negative breast cancer
Acetylation plays an important role in regulating the chaperone activity of heat shock protein 90 (Hsp90) during malignant transformation through the stabilization and conformational maturation of oncogenic proteins. However, the functional acetylation sites, potential anticancer drug targets, are s...
Autores principales: | Kou, Xinhui, Jiang, Xiaoxiao, Liu, Huijuan, Wang, Xuan, Sun, Fanghui, Han, Jiami, Fan, Jiaxing, Feng, Guize, Lin, Zhaohu, Jiang, Lan, Yang, Yonghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172049/ https://www.ncbi.nlm.nih.gov/pubmed/30039622 http://dx.doi.org/10.1111/cas.13748 |
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