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Collateral resistance to taxanes in enzalutamide‐resistant prostate cancer through aberrant androgen receptor and its variants

Currently, the optimal sequential use of androgen receptor (AR) axis‐targeted agents and taxane chemotherapies remains undetermined. We aimed to elucidate the resistance status between taxanes and enzalutamide, and the functional role of the AR axis. Enzalutamide‐resistant 22Rv1 cells showed collate...

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Detalles Bibliográficos
Autores principales: Shiota, Masaki, Dejima, Takashi, Yamamoto, Yoshiaki, Takeuchi, Ario, Imada, Kenjiro, Kashiwagi, Eiji, Inokuchi, Junichi, Tatsugami, Katsunori, Kajioka, Shunichi, Uchiumi, Takeshi, Eto, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172053/
https://www.ncbi.nlm.nih.gov/pubmed/30051622
http://dx.doi.org/10.1111/cas.13751