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Cytoplasmic liver kinase B1 promotes the growth of human lung adenocarcinoma by enhancing autophagy

Liver kinase B1 (LKB1) as a tumor suppression gene that is associated with various kinds of cancers, including lung cancer. In this study, we found that the effect of LKB1 on tumor growth was dependent on its subcellular expression in A549 and HCC827 cells. Full‐length LKB1 decreased the proliferati...

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Detalles Bibliográficos
Autores principales: Liu, Mengjie, Jiang, Lili, Fu, Xiao, Wang, Wenjuan, Ma, Jiequn, Tian, Tao, Nan, Kejun, Liang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172065/
https://www.ncbi.nlm.nih.gov/pubmed/30033530
http://dx.doi.org/10.1111/cas.13746