CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells

Circadian genes control most of the physiological functions in cancer cells, including cell proliferation, migration, and invasion. The CLOCK and BMAL1 complex plays a central role in circadian rhythms. Previous studies have shown that circadian genes may act as oncogenes or tumor-suppressor genes....

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Detalles Bibliográficos
Autores principales: Ma, Teng-jiao, Zhang, Zhi-wei, Lu, Yi-lu, Zhang, Ying-ying, Tao, Da-chang, Liu, Yun-qiang, Ma, Yong-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172197/
https://www.ncbi.nlm.nih.gov/pubmed/30287810
http://dx.doi.org/10.1038/s12276-018-0156-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172197/
https://www.ncbi.nlm.nih.gov/pubmed/30287810
http://dx.doi.org/10.1038/s12276-018-0156-4

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