Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers

The incidence of aggressive neuroendocrine prostate cancers (NEPC) related to androgen-deprivation therapy (ADT) is rising. NEPC is still poorly understood, such as its neuroendocrine differentiation (NED) and angiogenic phenotypes. Here we reveal that NED and angiogenesis are molecularly connected...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Zheng, Dayong, Zhou, Ting, Song, Haiping, Hulsurkar, Mohit, Su, Ning, Liu, Ying, Wang, Zheng, Shao, Long, Ittmann, Michael, Gleave, Martin, Han, Huanxing, Xu, Feng, Liao, Wangjun, Wang, Hongbo, Li, Wenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172226/
https://www.ncbi.nlm.nih.gov/pubmed/30287808
http://dx.doi.org/10.1038/s41467-018-06177-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172226/
https://www.ncbi.nlm.nih.gov/pubmed/30287808
http://dx.doi.org/10.1038/s41467-018-06177-2

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