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Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters

Persisters are a subpopulation of bacteria that are not killed by antibiotics even though they lack genetic resistance. Here we provide evidence that persisters can manifest as small colony variants (SCVs) in clinical infections. We analyze growth kinetics of Staphylococcus aureus sampled from in vi...

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Detalles Bibliográficos
Autores principales: Vulin, Clément, Leimer, Nadja, Huemer, Markus, Ackermann, Martin, Zinkernagel, Annelies S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172231/
https://www.ncbi.nlm.nih.gov/pubmed/30287875
http://dx.doi.org/10.1038/s41467-018-06527-0