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Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters
Persisters are a subpopulation of bacteria that are not killed by antibiotics even though they lack genetic resistance. Here we provide evidence that persisters can manifest as small colony variants (SCVs) in clinical infections. We analyze growth kinetics of Staphylococcus aureus sampled from in vi...
Autores principales: | Vulin, Clément, Leimer, Nadja, Huemer, Markus, Ackermann, Martin, Zinkernagel, Annelies S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172231/ https://www.ncbi.nlm.nih.gov/pubmed/30287875 http://dx.doi.org/10.1038/s41467-018-06527-0 |
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