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High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

Herein we introduce a high-throughput method, INTERFACE, to reveal the capacity of contiguous RNA nucleotides to establish in vivo intermolecular RNA interactions for the purpose of functional characterization of intracellular RNA. INTERFACE enables simultaneous accessibility interrogation of an unl...

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Detalles Bibliográficos
Autores principales: Mihailovic, Mia K., Vazquez-Anderson, Jorge, Li, Yan, Fry, Victoria, Vimalathas, Praveen, Herrera, Daniel, Lease, Richard A., Powell, Warren B., Contreras, Lydia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172242/
https://www.ncbi.nlm.nih.gov/pubmed/30287822
http://dx.doi.org/10.1038/s41467-018-06207-z