Cargando…

DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1

Mutations in SWI/SNF genes are amongst the most common across all human cancers, but efficient therapeutic approaches that exploit vulnerabilities caused by SWI/SNF mutations are currently lacking. Here, we show that the SWI/SNF ATPases BRM/SMARCA2 and BRG1/SMARCA4 promote the expression of p62/GTF2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ribeiro-Silva, Cristina, Aydin, Özge Z., Mesquita-Ribeiro, Raquel, Slyskova, Jana, Helfricht, Angela, Marteijn, Jurgen A., Hoeijmakers, Jan H. J., Lans, Hannes, Vermeulen, Wim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172278/ https://www.ncbi.nlm.nih.gov/pubmed/30287812 http://dx.doi.org/10.1038/s41467-018-06402-y

Ejemplares similares

Ubiquitin and TFIIH-stimulated DDB2 dissociation drives DNA damage handover in nucleotide excision repair
por: Ribeiro-Silva, Cristina, et al.
Publicado: (2020)

C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair
por: Thijssen, Karen L., et al.
Publicado: (2021)

Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled homologous recombination
por: Davó-Martínez, Carlota, et al.
Publicado: (2023)

SWI/SNF Infobase—An exclusive information portal for SWI/SNF remodeling complex subunits
por: Mani, Udayakumar, et al.
Publicado: (2017)

Emerging Themes in Mechanisms of Tumorigenesis by SWI/SNF Subunit Mutation
por: Jones, Cheyenne A., et al.
Publicado: (2022)

The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans
por: Tebbji, Faiza, et al.
Publicado: (2017)

The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors
por: Kahali, Bhaskar, et al.
Publicado: (2014)

MBRS-63. THE ROLE OF THE SWI/SNF COMPLEX SUBUNIT SMARCD3 IN MEDULLOBLASTOMA
por: Poore, Brad, et al.
Publicado: (2020)

Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma
por: Zhang, Zhenkun, et al.
Publicado: (2022)

ERCC1–XPF targeting to psoralen–DNA crosslinks depends on XPA and FANCD2
por: Sabatella, Mariangela, et al.
Publicado: (2019)

A new, highly conserved domain in Swi2/Snf2 is required for SWI/SNF remodeling
por: Sen, Payel, et al.
Publicado: (2011)

Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage
por: Slyskova, Jana, et al.
Publicado: (2018)

Caenorhabditis elegans SWI/SNF Subunits Control Sequential Developmental Stages in the Somatic Gonad
por: Large, Edward E., et al.
Publicado: (2014)

Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing
por: Reddy, Divya, et al.
Publicado: (2022)

Involvement of Global Genome Repair, Transcription Coupled Repair, and Chromatin Remodeling in UV DNA Damage Response Changes during Development
por: Lans, Hannes, et al.
Publicado: (2010)

ATP-dependent chromatin remodeling in the DNA-damage response
por: Lans, Hannes, et al.
Publicado: (2012)

Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features
por: Sabatella, Mariangela, et al.
Publicado: (2018)

SWI/SNF proteins as targets in cancer therapy
por: Schiaffino-Ortega, Santiago, et al.
Publicado: (2014)

Architecture of SWI/SNF chromatin remodeling complex
por: Zhang, Zhihui, et al.
Publicado: (2018)

SWI/SNF Alterations in Squamous Bladder Cancers
por: Achenbach, Fabian, et al.
Publicado: (2020)

SWI/SNF Chromatin Remodeling Enzymes in Melanoma
por: Dreier, Megan R., et al.
Publicado: (2022)

Mechanism of action of the SWI/SNF family complexes
por: Chen, Kangjing, et al.
Publicado: (2023)

Advances in the role of SWI/SNF complexes in tumours
por: Li, Ziwei, et al.
Publicado: (2023)

Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development
por: Marquez-Vilendrer, Stefanie B., et al.
Publicado: (2016)

The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function
por: Wischhof, Lena, et al.
Publicado: (2017)

SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility
por: Abedini, Atefeh, et al.
Publicado: (2022)

BCL7B, a SWI/SNF complex subunit, orchestrates cancer immunity and stemness
por: Higuchi, Sayaka, et al.
Publicado: (2023)

The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit
por: Zraly, Claudia B., et al.
Publicado: (2012)

The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair
por: Barnett, Jamie T, et al.
Publicado: (2020)

ISWI chromatin remodeling complexes in the DNA damage response
por: Aydin, Özge Z, et al.
Publicado: (2014)

Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription
por: Aydin, Özge Z., et al.
Publicado: (2014)

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers
por: Kelso, Timothy W R, et al.
Publicado: (2017)

Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits
por: Raab, Jesse R., et al.
Publicado: (2017)

Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer
por: Wang, Qingying, et al.
Publicado: (2021)

Correction to: SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility
Publicado: (2023)

Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
por: Sun, Jie, et al.
Publicado: (2023)

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers
por: Shain, A. Hunter, et al.
Publicado: (2013)

The clinical significance of SWI/SNF complex in pancreatic cancer
por: NUMATA, MASAKATSU, et al.
Publicado: (2012)

Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2019)

(mis)-Targeting of SWI/SNF complex(es) in cancer
por: Reddy, Divya, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mm9j9r8ltt657pj4k3ltacdm50