Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

Although genome-wide association studies (GWAS) for prostate cancer (PrCa) have identified more than 100 risk regions, most of the risk genes at these regions remain largely unknown. Here we integrate the largest PrCa GWAS (N = 142,392) with gene expression measured in 45 tissues (N = 4458), includi...

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Detalles Bibliográficos
Autores principales: Mancuso, Nicholas, Gayther, Simon, Gusev, Alexander, Zheng, Wei, Penney, Kathryn L., Kote-Jarai, Zsofia, Eeles, Rosalind, Freedman, Matthew, Haiman, Christopher, Pasaniuc, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172280/
https://www.ncbi.nlm.nih.gov/pubmed/30287866
http://dx.doi.org/10.1038/s41467-018-06302-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172280/
https://www.ncbi.nlm.nih.gov/pubmed/30287866
http://dx.doi.org/10.1038/s41467-018-06302-1

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