Mutation pattern analysis reveals polygenic mini-drivers associated with relapse after surgery in lung adenocarcinoma

The genomic lesions found in malignant tumours exhibit a striking degree of heterogeneity. Many tumours lack a known driver mutation, and their genetic basis is unclear. By mapping the somatic mutations identified in primary lung adenocarcinomas onto an independent coexpression network derived from...

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Detalles Bibliográficos
Autores principales: Bennett, Laura, Howell, Matthew, Memon, Danish, Smowton, Chris, Zhou, Cong, Miller, Crispin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172282/
https://www.ncbi.nlm.nih.gov/pubmed/30287876
http://dx.doi.org/10.1038/s41598-018-33276-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172282/
https://www.ncbi.nlm.nih.gov/pubmed/30287876
http://dx.doi.org/10.1038/s41598-018-33276-3

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