Overexpression of Optic Atrophy Type 1 Protects Retinal Ganglion Cells and Upregulates Parkin Expression in Experimental Glaucoma

Glaucoma is a neurodegenerative disease that features progressive loss of retinal ganglion cells (RGCs). Increasing evidences have revealed that impaired mitochondrial dynamics occurs early in neurodegenerative diseases. Optic Atrophy Type 1 (OPA1), a mitochondrial fusion protein, has recently been...

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Detalles Bibliográficos
Autores principales: Hu, Xinxin, Dai, Yi, Zhang, Rong, Shang, Kunte, Sun, Xinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172338/
https://www.ncbi.nlm.nih.gov/pubmed/30323741
http://dx.doi.org/10.3389/fnmol.2018.00350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172338/
https://www.ncbi.nlm.nih.gov/pubmed/30323741
http://dx.doi.org/10.3389/fnmol.2018.00350

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