Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels

Redox active selenium (Se) compounds at sub toxic doses act as pro-oxidants with cytotoxic effects on tumor cells and are promising future chemotherapeutic agents. However, little is known about how Se compounds affect immune cells in the tumor microenvironment. We demonstrate that the inorganic Se...

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Detalles Bibliográficos
Autores principales: Nair, Deepika, Rådestad, Emelie, Khalkar, Prajakta, Diaz-Argelich, Nuria, Schröder, Axel, Klynning, Charlotte, Ungerstedt, Johanna, Uhlin, Michael, Fernandes, Aristi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172341/
https://www.ncbi.nlm.nih.gov/pubmed/30324091
http://dx.doi.org/10.3389/fonc.2018.00407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172341/
https://www.ncbi.nlm.nih.gov/pubmed/30324091
http://dx.doi.org/10.3389/fonc.2018.00407

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