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BACE1 gene silencing alleviates isoflurane anesthesia-induced postoperative cognitive dysfunction in immature rats by activating the PI3K/Akt signaling pathway

Postoperative cognitive dysfunction (POCD) is a severe complication characterized by cognitive dysfunction following anesthesia and surgery. The aim of the present study was to investigate the effects of β-site amyloid precursor protein cleavage enzyme 1 (BACE1) gene silencing on isoflurane anesthes...

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Detalles Bibliográficos
Autores principales: Wang, Ying-Bin, Xie, Jian-Qin, Liu, Wei, Zhang, Rong-Zhi, Huang, Sheng-Hui, Xing, Yan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172366/
https://www.ncbi.nlm.nih.gov/pubmed/30221701
http://dx.doi.org/10.3892/mmr.2018.9453