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FKBP11 protects intestinal epithelial cells against inflammation-induced apoptosis via the JNK-caspase pathway in Crohn's disease

Endoplasmic reticulum (ER) stress in intestinal epithelial cells (IECs) has an important role in the pathogenesis of Crohn's disease (CD). FK506 binding protein 11 (FKBP11), a member of the peptidyl-prolyl cis-trans isomerase family, is involved in the unfolded protein response (UPR) and is clo...

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Detalles Bibliográficos
Autores principales: Wang, Xiaotong, Cui, Xiaopeng, Zhu, Chuanwu, Li, Ming, Zhao, Juan, Shen, Zhongyi, Shan, Xiaohang, Wang, Liang, Wu, Han, Shen, Yanting, Ni, You, Zhang, Dongmei, Zhou, Guoxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172375/
https://www.ncbi.nlm.nih.gov/pubmed/30221722
http://dx.doi.org/10.3892/mmr.2018.9485