Adoptive transfer of xenoantigen-stimulated T cell receptor Vβ-restricted human regulatory T cells prevents porcine islet xenograft rejection in humanized mice

Polyclonal expansion of human regulatory T cells (Tregs) prevents xenogeneic rejection by suppressing effector T cell responses in vitro and in vivo. However, a major limitation to using polyclonally expanded Tregs is that they may cause pan-immunosuppressive effects. The present study was conducted...

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Detalles Bibliográficos
Autores principales: Jin, Xi, Hu, Min, Gong, Lina, Li, Huifang, Wang, Yan, Ji, Ming, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172378/
https://www.ncbi.nlm.nih.gov/pubmed/30221725
http://dx.doi.org/10.3892/mmr.2018.9471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172378/
https://www.ncbi.nlm.nih.gov/pubmed/30221725
http://dx.doi.org/10.3892/mmr.2018.9471

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