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DNA damage‐induced replication stress results in PA200‐proteasome‐mediated degradation of acetylated histones

Histone acetylation influences protein interactions and chromatin accessibility and plays an important role in the regulation of transcription, replication, and DNA repair. Conversely, DNA damage affects these crucial cellular processes and induces changes in histone acetylation. However, a comprehe...

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Detalles Bibliográficos
Autores principales: Mandemaker, Imke K, Geijer, Marit E, Kik, Iris, Bezstarosti, Karel, Rijkers, Erikjan, Raams, Anja, Janssens, Roel C, Lans, Hannes, Hoeijmakers, Jan HJ, Demmers, Jeroen AA, Vermeulen, Wim, Marteijn, Jurgen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172457/
https://www.ncbi.nlm.nih.gov/pubmed/30104204
http://dx.doi.org/10.15252/embr.201745566