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Metformin Protects against H(2)O(2)-Induced Cardiomyocyte Injury by Inhibiting the miR-1a-3p/GRP94 Pathway

Ischemia-reperfusion (I/R) injury is a major side effect of the reperfusion treatment of the ischemic heart. Few therapies are available for the effective prevention of this injury caused by the oxidative stress-induced cardiomyocyte apoptosis. Metformin was shown to have a potential cardiac protect...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Liu, Xue, Zhang, Lu, Li, Xuelian, Zhou, Zhongqiu, Jiao, Lei, Shao, Yingchun, Li, Mengmeng, Leng, Bing, Zhou, Yuhong, Liu, Tianyi, Liu, Qiushuang, Shan, Hongli, Du, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172474/
https://www.ncbi.nlm.nih.gov/pubmed/30292140
http://dx.doi.org/10.1016/j.omtn.2018.09.001