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Metformin Protects against H(2)O(2)-Induced Cardiomyocyte Injury by Inhibiting the miR-1a-3p/GRP94 Pathway
Ischemia-reperfusion (I/R) injury is a major side effect of the reperfusion treatment of the ischemic heart. Few therapies are available for the effective prevention of this injury caused by the oxidative stress-induced cardiomyocyte apoptosis. Metformin was shown to have a potential cardiac protect...
Autores principales: | Zhang, Ying, Liu, Xue, Zhang, Lu, Li, Xuelian, Zhou, Zhongqiu, Jiao, Lei, Shao, Yingchun, Li, Mengmeng, Leng, Bing, Zhou, Yuhong, Liu, Tianyi, Liu, Qiushuang, Shan, Hongli, Du, Zhimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172474/ https://www.ncbi.nlm.nih.gov/pubmed/30292140 http://dx.doi.org/10.1016/j.omtn.2018.09.001 |
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