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Genetic variants predicting aerobic capacity response to training are also associated with skeletal muscle oxidative capacity in moderate-to-severe COPD

Muscle oxidative capacity is a major determinant of maximum oxygen uptake (V̇O(2max)). V̇O(2max) predicts survival in humans. Muscle oxidative capacity is low in chronic obstructive pulmonary disease (COPD) and can be assessed from the muscle oxygen consumption recovery rate constant (k) by near-inf...

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Detalles Bibliográficos
Autores principales: Adami, Alessandra, Hobbs, Brian D., McDonald, Merry-Lynn N., Casaburi, Richard, Rossiter, Harry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172613/
https://www.ncbi.nlm.nih.gov/pubmed/29799805
http://dx.doi.org/10.1152/physiolgenomics.00140.2017