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Interplay of Histone Marks with Serine ADP-Ribosylation

Serine ADP-ribosylation (Ser-ADPr) is a recently discovered protein modification that is catalyzed by PARP1 and PARP2 when in complex with the eponymous histone PARylation factor 1 (HPF1). In addition to numerous other targets, core histone tails are primary acceptors of Ser-ADPr in the DNA damage r...

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Detalles Bibliográficos
Autores principales: Bartlett, Edward, Bonfiglio, Juan José, Prokhorova, Evgeniia, Colby, Thomas, Zobel, Florian, Ahel, Ivan, Matic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172693/
https://www.ncbi.nlm.nih.gov/pubmed/30257210
http://dx.doi.org/10.1016/j.celrep.2018.08.092