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RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency
BACKGROUND: Current antiretroviral therapy is effective in controlling HIV-1 infection. However, cessation of therapy is associated with rapid return of viremia from the viral reservoir. Eradicating the HIV-1 reservoir has proven difficult with the limited success of latency reactivation strategies...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172763/ https://www.ncbi.nlm.nih.gov/pubmed/30286764 http://dx.doi.org/10.1186/s12977-018-0451-0 |