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RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency

BACKGROUND: Current antiretroviral therapy is effective in controlling HIV-1 infection. However, cessation of therapy is associated with rapid return of viremia from the viral reservoir. Eradicating the HIV-1 reservoir has proven difficult with the limited success of latency reactivation strategies...

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Detalles Bibliográficos
Autores principales: Méndez, Catalina, Ledger, Scott, Petoumenos, Kathy, Ahlenstiel, Chantelle, Kelleher, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172763/
https://www.ncbi.nlm.nih.gov/pubmed/30286764
http://dx.doi.org/10.1186/s12977-018-0451-0