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The hsa-miR-181a-5p reduces oxidation resistance by controlling SECISBP2 in osteoarthritis

BACKGROUND: The phenotypes of osteoarthritis (OA) consist of cartilage extracellular matrix (ECM) metabolism disorder and the breakdown of cartilage homeostasis, which are induced by pro-inflammatory factors and oxidative stress. Selenoproteins regulated by selenocysteine insertion sequence binding...

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Detalles Bibliográficos
Autores principales: Xue, Jianli, Min, Zixin, Xia, Zhuqing, Cheng, Bin, Lan, Binshang, Zhang, Fujun, Han, Yan, Wang, Kunzheng, Sun, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172777/
https://www.ncbi.nlm.nih.gov/pubmed/30286747
http://dx.doi.org/10.1186/s12891-018-2273-6