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Inverse association between estrogen receptor-α DNA methylation and breast composition in adolescent Chilean girls

BACKGROUND: Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The influence of epigenetic regulation of ER-α on adolescent breast composition has not been previously studied and could serve as a marker of...

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Detalles Bibliográficos
Autores principales: Binder, Alexandra M, Stiemsma, Leah T, Keller, Kristen, van Otterdijk, Sanne D, Mericq, Verónica, Pereira, Ana, Santos, José L, Shepherd, John, Michels, Karin B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172836/
https://www.ncbi.nlm.nih.gov/pubmed/30286806
http://dx.doi.org/10.1186/s13148-018-0553-5