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Inverse association between estrogen receptor-α DNA methylation and breast composition in adolescent Chilean girls
BACKGROUND: Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The influence of epigenetic regulation of ER-α on adolescent breast composition has not been previously studied and could serve as a marker of...
Autores principales: | Binder, Alexandra M, Stiemsma, Leah T, Keller, Kristen, van Otterdijk, Sanne D, Mericq, Verónica, Pereira, Ana, Santos, José L, Shepherd, John, Michels, Karin B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172836/ https://www.ncbi.nlm.nih.gov/pubmed/30286806 http://dx.doi.org/10.1186/s13148-018-0553-5 |
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