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Hypoxic Preconditioning Maintains GLT-1 Against Transient Global Cerebral Ischemia Through Upregulating Cx43 and Inhibiting c-Src

Transient global cerebral ischemia (tGCI) causes excessive release of glutamate from neurons. Astrocytic glutamate transporter-1 (GLT-1) and glutamine synthetase (GS) together play a predominant role in maintaining glutamate at normal extracellular concentrations. Though our previous studies reporte...

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Detalles Bibliográficos
Autores principales: Li, Kongping, Zhou, Huarong, Zhan, Lixuan, Shi, Zhe, Sun, Weiwen, Liu, Dandan, Liu, Liu, Liang, Donghai, Tan, Yafu, Xu, Wensheng, Xu, En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172853/
https://www.ncbi.nlm.nih.gov/pubmed/30323740
http://dx.doi.org/10.3389/fnmol.2018.00344