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Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships

Synapses are fundamental units of communication in the brain. The prototypical synapse-organizing complex neurexin-neuroligin mediates synapse development and function and is central to a shared genetic risk pathway in autism and schizophrenia. Neurexin’s role in synapse development is thought to be...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Lu, Hong, Peixoto, Rui T., Pines, Mary K., Ge, Yuan, Oku, Shinichiro, Siddiqui, Tabrez J., Xie, Yicheng, Wu, Wenlan, Archer-Hartmann, Stephanie, Yoshida, Keitaro, Tanaka, Kenji F., Aricescu, A. Radu, Azadi, Parastoo, Gordon, Michael D., Sabatini, Bernardo L., Wong, Rachel O.L., Craig, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173057/
https://www.ncbi.nlm.nih.gov/pubmed/30100184
http://dx.doi.org/10.1016/j.cell.2018.07.002