ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling

Genome-scale metabolic models (GEMs) are comprehensive descriptions of cell metabolism and have been extensively used to understand biological responses in health and disease. One such application is in determining metabolic adaptation to the absence of a gene or reaction, i.e., essentiality analysi...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Bidkhori, Gholamreza, Benfeitas, Rui, Lee, Sunjae, Arif, Muhammad, Uhlén, Mathias, Mardinoglu, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173058/
https://www.ncbi.nlm.nih.gov/pubmed/30323767
http://dx.doi.org/10.3389/fphys.2018.01355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173058/
https://www.ncbi.nlm.nih.gov/pubmed/30323767
http://dx.doi.org/10.3389/fphys.2018.01355

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