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The evolution and diversity of the nonsense-mediated mRNA decay pathway

Nonsense-mediated mRNA decay is a eukaryotic pathway that degrades transcripts with premature termination codons (PTCs). In most eukaryotes, thousands of transcripts are degraded by NMD, including many important regulators of developmental and stress response pathways. Transcripts can be targeted to...

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Detalles Bibliográficos
Autor principal: Lloyd, James P. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173133/
https://www.ncbi.nlm.nih.gov/pubmed/30345031
http://dx.doi.org/10.12688/f1000research.15872.2