DNA G-quadruplex structures mould the DNA methylome

Control of DNA methylation level is critical for gene regulation, and the factors that govern hypomethylation at CpG islands (CGIs) are still being uncovered. Here, we provide evidence that G-quadruplex (G4) DNA secondary structures are genomic features that influence methylation at CGIs. We show th...

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Detalles Bibliográficos
Autores principales: Mao, Shi-Qing, Ghanbarian, Avazeh T., Spiegel, Jochen, Cuesta, Sergio Martínez, Beraldi, Dario, Di Antonio, Marco, Marsico, Giovanni, Hänsel-Hertsch, Robert, Tannahill, David, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173298/
https://www.ncbi.nlm.nih.gov/pubmed/30275516
http://dx.doi.org/10.1038/s41594-018-0131-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173298/
https://www.ncbi.nlm.nih.gov/pubmed/30275516
http://dx.doi.org/10.1038/s41594-018-0131-8

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