Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme

We have previously shown that the nucleocytoplasmic carrier karyopherin a2 (KPNA2) is overexpressed in glioblastoma multiforme (GBM) whereas its expression is inversely associated with patient prognosis. However, the promoting role of KPNA2 in gliomagenesis is still poorly understood. This study aim...

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Detalles Bibliográficos
Autores principales: Martinez-Olivera, Ramon, Datsi, Angeliki, Stallkamp, Maren, Köller, Manfred, Kohtz, Isabelle, Pintea, Bogdan, Gousias, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173355/
https://www.ncbi.nlm.nih.gov/pubmed/30323892
http://dx.doi.org/10.18632/oncotarget.26033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173355/
https://www.ncbi.nlm.nih.gov/pubmed/30323892
http://dx.doi.org/10.18632/oncotarget.26033

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