Cargando…

Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme

We have previously shown that the nucleocytoplasmic carrier karyopherin a2 (KPNA2) is overexpressed in glioblastoma multiforme (GBM) whereas its expression is inversely associated with patient prognosis. However, the promoting role of KPNA2 in gliomagenesis is still poorly understood. This study aim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martinez-Olivera, Ramon, Datsi, Angeliki, Stallkamp, Maren, Köller, Manfred, Kohtz, Isabelle, Pintea, Bogdan, Gousias, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173355/ https://www.ncbi.nlm.nih.gov/pubmed/30323892 http://dx.doi.org/10.18632/oncotarget.26033

Ejemplares similares

Nucleocytoplasmic Shuttling of Endocytic Proteins
por: Vecchi, Manuela, et al.
Publicado: (2001)

Nucleocytoplasmic Shuttling Activity of Ataxin-3
por: Macedo-Ribeiro, Sandra, et al.
Publicado: (2009)

The Rules and Functions of Nucleocytoplasmic Shuttling Proteins
por: Fu, Xuekun, et al.
Publicado: (2018)

Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport
por: Huang, Hsiao-Yun, et al.
Publicado: (2014)

Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage
por: Kalita, Joanna, et al.
Publicado: (2022)

Evolution of the Karyopherin-β Family of Nucleocytoplasmic Transport Factors; Ancient Origins and Continued Specialization
por: O'Reilly, Amanda J., et al.
Publicado: (2011)

Stroke-derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps
por: Datsi, Angeliki, et al.
Publicado: (2022)

Correction to: Stroke‑derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps
por: Datsi, Angeliki, et al.
Publicado: (2023)

Nucleocytoplasmic Shuttling of Influenza A Virus Proteins
por: Li, Jing, et al.
Publicado: (2015)

Nucleocytoplasmic Shuttling of STATs. A Target for Intervention?
por: Ernst, Sabrina, et al.
Publicado: (2019)

The POU protein Oct-6 is a nucleocytoplasmic shuttling protein
por: Baranek, Constanze, et al.
Publicado: (2005)

Nucleocytoplasmic Shuttling of Cytoskeletal Proteins: Molecular Mechanism and Biological Significance
por: Kumeta, Masahiro, et al.
Publicado: (2012)

P68 RNA Helicase Is A Nucleocytoplasm Shuttling Protein
por: Wang, Haizhen, et al.
Publicado: (2009)

Identification of a Novel Nucleocytoplasmic Shuttling RNA Helicase of Trypanosomes
por: Inoue, Alexandre Haruo, et al.
Publicado: (2014)

Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection
por: Honda, Tomoyuki, et al.
Publicado: (2013)

Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
por: Aas, Aleksander, et al.
Publicado: (2017)

Characterization of Nucleocytoplasmic Shuttling of Pseudorabies Virus Protein UL46
por: Xu, Jing-jing, et al.
Publicado: (2020)

Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry
por: Braun, Klaus, et al.
Publicado: (2009)

Molecular characterization of subcellular localization and nucleocytoplasmic shuttling of PRV UL54
por: Li, Meili, et al.
Publicado: (2011)

Novel evidence for the nucleocytoplasmic shuttling of HIV-1 Tat by Importin13
por: Woods, Elena, et al.
Publicado: (2013)

Protein kinase Cα regulates the nucleocytoplasmic shuttling of KRIT1
por: De Luca, Elisa, et al.
Publicado: (2021)

Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
por: Gousias, Konstantinos, et al.
Publicado: (2022)

An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export
por: Kendirgi, Frederic, et al.
Publicado: (2003)

Nucleocytoplasmic Shuttling of the Cdc42p Exchange Factor Cdc24p
por: Nern, Aljoscha, et al.
Publicado: (2000)

Functional comparison of protein domains within aPKCs involved in nucleocytoplasmic shuttling
por: Seidl, Sebastian, et al.
Publicado: (2012)

Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling
por: Jiao, Baowei, et al.
Publicado: (2013)

Nucleocytoplasmic shuttling of SOX14A and SOX14B transcription factors
por: She, Zhen-Yu, et al.
Publicado: (2017)

Nucleocytoplasmic shuttling of Gle1 impacts DDX1 at transcription termination sites
por: Sharma, Manisha, et al.
Publicado: (2020)

Dendritic Cell Vaccination of Glioblastoma: Road to Success or Dead End
por: Datsi, Angeliki, et al.
Publicado: (2021)

Karyopherin α deficiency contributes to human preimplantation embryo arrest
por: Wang, Wenjing, et al.
Publicado: (2023)

Importin/exportin-mediated nucleocytoplasmic shuttling of cucumber mosaic virus 2b protein is required for 2b’s efficient suppression of RNA silencing
por: Kim, Hangil, et al.
Publicado: (2022)

Nucleocytoplasmic Shuttling of Histone Deacetylase 9 Controls Activity-Dependent Thalamocortical Axon Branching
por: Alchini, Ricardo, et al.
Publicado: (2017)

Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α
por: Moriyama, Tetsuji, et al.
Publicado: (2020)

Nucleocytoplasmic Shuttling Factors Including Ran and CRM1 Mediate Nuclear Export of NFAT In Vitro
por: Kehlenbach, Ralph H., et al.
Publicado: (1998)

Nucleocytoplasmic shuttling of tRNAs and implication of the cytosolic Hsp70 system in tRNA import
por: Yoshihisa, Tohru
Publicado: (2015)

Analysis of the nucleocytoplasmic shuttling RNA-binding protein HNRNPU using optimized HITS-CLIP method
por: Yugami, Masato, et al.
Publicado: (2020)

Karyopherins play the field
por: Leslie, Mitch
Publicado: (2006)

Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinoma
por: Yang, Yunfeng, et al.
Publicado: (2017)

hMSH5 is a nucleocytoplasmic shuttling protein whose stability depends on its subcellular localization
por: Lahaye, François, et al.
Publicado: (2010)

Subcellular Localization of Class II HDAs in Arabidopsis thaliana: Nucleocytoplasmic Shuttling of HDA15 Is Driven by Light
por: Alinsug, Malona V., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pb6qgh4bovgpj4887k18po37o5