Cargando…

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma

Increasing evidence links Notch-1 signaling with the maintenance of intestinal architecture and homeostasis. Dysfunction in the common Notch-1 pathway transcription factor recombinant binding protein suppressor of hairless (RBP-J) is associated with loss of epithelial barrier integrity and aberrant...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunkin, David, Iuga, Alina C., Mimouna, Sanda, Harris, Carolyn L., Haure-Mirande, Jean-Vianney, Bozec, Dominique, Yeretssian, Garabet, Dahan, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173356/
https://www.ncbi.nlm.nih.gov/pubmed/30323897
http://dx.doi.org/10.18632/oncotarget.26086