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In vitro and ex-vivo evaluation of topical formulations designed to minimize transdermal absorption of Vitamin K1
Topical application of Vitamin K1 has been demonstrated to effectively treat papulopustular skin rash, a serious and frequently encountered side effect of Epidermal Growth Factor Inhibitors (EGFRIs). Systemic absorption of vitamin K1 from skin and the resultant consequence of antagonizing EGFRIs ant...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173387/ https://www.ncbi.nlm.nih.gov/pubmed/30289881 http://dx.doi.org/10.1371/journal.pone.0204531 |