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In vitro and ex-vivo evaluation of topical formulations designed to minimize transdermal absorption of Vitamin K1

Topical application of Vitamin K1 has been demonstrated to effectively treat papulopustular skin rash, a serious and frequently encountered side effect of Epidermal Growth Factor Inhibitors (EGFRIs). Systemic absorption of vitamin K1 from skin and the resultant consequence of antagonizing EGFRIs ant...

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Detalles Bibliográficos
Autores principales: Nabiee, Ramina, Dubois, Barent, Green, Laura, Sharma, Ajay, Wong, Siu Fun, Montazeri Aliabadi, Hamidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173387/
https://www.ncbi.nlm.nih.gov/pubmed/30289881
http://dx.doi.org/10.1371/journal.pone.0204531