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Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold
This paper describes the synthesis and anticholinesterase potency of Cinchona-based alkaloids; ten quaternary derivatives of cinchonines and their corresponding pseudo-enantiomeric cinchonidines. The quaternization of quinuclidine moiety of each compound was carried out with groups diverse in their...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173406/ https://www.ncbi.nlm.nih.gov/pubmed/30289893 http://dx.doi.org/10.1371/journal.pone.0205193 |