Toxicity of JQ1 in neuronal derivatives of human umbilical cord mesenchymal stem cells

Bromodomain and extra-terminal domain (BET) proteins regulate the transcription of many genes including c-MYC, a proto-oncogene, which is upregulated in many types of cancers. The thienodiazepine class of BET inhibitors, such as JQ1, inhibits growth of cancer cells and triggers apoptosis. However, t...

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Detalles Bibliográficos
Autores principales: Bakshi, Shreeya, McKee, Christina, Walker, Keegan, Brown, Christina, Chaudhry, G. Rasul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173460/
https://www.ncbi.nlm.nih.gov/pubmed/30333915
http://dx.doi.org/10.18632/oncotarget.26127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173460/
https://www.ncbi.nlm.nih.gov/pubmed/30333915
http://dx.doi.org/10.18632/oncotarget.26127

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