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Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands

[Image: see text] The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) support the survival and functioning of various neuronal populations. Thus, they could be attractive therapeutic agents against a multitude of neurodegenerative diseases caused by progressive death of GFLs...

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Detalles Bibliográficos
Autores principales: Ivanova, Larisa, Tammiku-Taul, Jaana, García-Sosa, Alfonso T., Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173496/
https://www.ncbi.nlm.nih.gov/pubmed/30320260
http://dx.doi.org/10.1021/acsomega.8b01524