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Novel multiplex PCR-SSP method for centromeric KIR allele discrimination

Allelic diversity of the KIR2DL receptors drive differential expression and ligand-binding affinities that impact natural killer cell function and patient outcomes for diverse cancers. We have developed a global intermediate resolution amplification-refractory mutation system (ARMS) PCR-SSP method f...

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Detalles Bibliográficos
Autores principales: Le Luduec, Jean-Benoît, Kudva, Anupa, Boudreau, Jeanette E., Hsu, Katharine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173694/
https://www.ncbi.nlm.nih.gov/pubmed/30291273
http://dx.doi.org/10.1038/s41598-018-33135-1