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Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis
Porphyromonas gingivalis is a keystone bacterial pathogen of chronic periodontitis. P. gingivalis is unable to synthesise the porphyrin macrocycle and relies on exogenous porphyrin, including haem or haem biosynthesis intermediates from host sources. We show that under the iron-limited conditions pr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173696/ https://www.ncbi.nlm.nih.gov/pubmed/30291238 http://dx.doi.org/10.1038/s41467-018-06470-0 |