Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis

Porphyromonas gingivalis is a keystone bacterial pathogen of chronic periodontitis. P. gingivalis is unable to synthesise the porphyrin macrocycle and relies on exogenous porphyrin, including haem or haem biosynthesis intermediates from host sources. We show that under the iron-limited conditions pr...

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Detalles Bibliográficos
Autores principales: Gao, Jin-Long, Kwan, Ann H., Yammine, Anthony, Zhou, Xiaoyan, Trewhella, Jill, Hugrass, Barbara M., Collins, Daniel A. T., Horne, James, Ye, Ping, Harty, Derek, Nguyen, Ky-Anh, Gell, David A., Hunter, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173696/
https://www.ncbi.nlm.nih.gov/pubmed/30291238
http://dx.doi.org/10.1038/s41467-018-06470-0

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