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Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88

Host pathways mediating changes in immune states elicited by intestinal microbial colonization are incompletely characterized. Here we describe alterations of the host immune state induced by colonization of germ-free zebrafish larvae with an intestinal microbial community or single bacterial specie...

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Detalles Bibliográficos
Autores principales: Koch, Bjørn E. V., Yang, Shuxin, Lamers, Gerda, Stougaard, Jens, Spaink, Herman P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173721/
https://www.ncbi.nlm.nih.gov/pubmed/30291253
http://dx.doi.org/10.1038/s41467-018-06658-4