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Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus

Genome-wide DNA methylation has been implicated in complex human diseases. Here, we identified epigenetic biomarkers for type 2 diabetes (T2D) underlying obesogenic environments. In a blood-based DNA methylation analysis of 11 monozygotic twins (MZTW) discordant for T2D, we discovered genetically in...

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Detalles Bibliográficos
Autores principales: Hwang, Joo-Yeon, Lee, Hyo Jung, Go, Min Jin, Jang, Han Byul, Choi, Nak-Hyun, Bae, Jae Bum, Castillo-Fernandez, Juan E., Bell, Jordana T., Spector, Tim D., Lee, Hye-Ja, Kim, Bong-Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173741/
https://www.ncbi.nlm.nih.gov/pubmed/30291282
http://dx.doi.org/10.1038/s41598-018-33238-9