The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue

Obesity and related metabolic pathologies represent a significant public health concern. Obesity is associated with increased oxidative stress that damages genomic and mitochondrial DNA. Oxidatively-induced lesions in both DNA pools are repaired via the base-excision repair pathway, initiated by DNA...

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Detalles Bibliográficos
Autores principales: Komakula, Sai Santosh Babu, Tumova, Jana, Kumaraswamy, Deeptha, Burchat, Natalie, Vartanian, Vladimir, Ye, Hong, Dobrzyn, Agnieszka, Lloyd, R. Stephen, Sampath, Harini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173743/
https://www.ncbi.nlm.nih.gov/pubmed/30291284
http://dx.doi.org/10.1038/s41598-018-33151-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173743/
https://www.ncbi.nlm.nih.gov/pubmed/30291284
http://dx.doi.org/10.1038/s41598-018-33151-1

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