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Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2
Toxic protein aggregates are key features of progressive neurodegenerative diseases. In addition to “seed” proteins diagnostic for each neuropathy (e.g., Aβ(1–42) and tau in Alzheimer’s disease), aggregates contain numerous other proteins, many of which are common to aggregates from diverse diseases...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173753/ https://www.ncbi.nlm.nih.gov/pubmed/30291272 http://dx.doi.org/10.1038/s41598-018-33143-1 |