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Bone protection by inhibition of microRNA-182

Targeting microRNAs recently shows significant therapeutic promise; however, such progress is underdeveloped in treatment of skeletal diseases with osteolysis, such as osteoporosis and rheumatoid arthritis (RA). Here, we identified miR-182 as a key osteoclastogenic regulator in bone homeostasis and...

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Detalles Bibliográficos
Autores principales: Inoue, Kazuki, Deng, Zhonghao, Chen, Yufan, Giannopoulou, Eugenia, Xu, Ren, Gong, Shiaoching, Greenblatt, Matthew B., Mangala, Lingegowda S., Lopez-Berestein, Gabriel, Kirsch, David G., Sood, Anil K., Zhao, Liang, Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173760/
https://www.ncbi.nlm.nih.gov/pubmed/30291236
http://dx.doi.org/10.1038/s41467-018-06446-0